How GLP-1 Drugs Can Change People’s Cravings and Eating Patterns

Glucagon-like peptide-1 (GLP-1) receptor agonists like semaglutide have been gaining considerable attention for their ability to help people manage and lose weight. Ozempic® is the brand name for Novo Nordisk’s drug semaglutide, while Mounjaro® is the brand name for Eli Lilly’s drug tirzepatide. Tirzepatide also works on another receptor in the body, gastric inhibitory polypetide (GIP) to aid in decreasing appetite. When used exclusively for weight loss, Ozempic® is marketed under the brand name Wegovy®, while Mounjaro® goes by the brand name Zepbound®.

Beyond their role in managing blood sugar (glucose) levels and suppressing appetite, new research indicates that “GLP-1s” may also influence individuals’ food and drink cravings and consumption. People are reporting not only a reduced intake of food, but also a diminished desire for alcohol.

Why People Are Eating and Drinking Less on GLP-1s

These medications mimic the GLP-1 hormone that is released after eating and drinking, as result you have they have multiple effects that aid in weight loss. suppresses The main way these medicationsGLP-1 receptors help slow down how quickly your stomach empties, making you feel full for longer. This sends signals to your brain that you’re satisfied, which can reduce your appetite and usually leads to eating fewer calories overall.

In addition to their effects on appetite, GLPs also appear to impact the brain’s reward system, which plays a crucial role in craving and addictive behaviors.

A new study published in JAMA Psychiatry looked at whether taking semaglutide reduced alcohol consumption and craving in adults with alcohol use disorder (AUD). The medical trial involved 48 individuals with AUD, most of whom had a body mass index (BMI) over 30. Over a nine-week period, half of the participants received semaglutide and half a placebo.

Those who took semaglutide didn’t reduce the actual number of days they drank , however they did consume less alcohol overall by the end of the study compared to those given a placebo. The results indicate that similar to semaglutides’ reduction in food cravings to aid weight loss, the desire or craving for alcohol may also be weakened.  Future research may include investigation into use of these agents for substance use disorder as well.

These findings highlight the potential of GLP-1 drugs beyond weight loss, suggesting they can play an important role in treating substance use disorders by influencing the brain’s reward  pathways. These medications may become an important tool for addressing both metabolic health and compulsive behaviors, offering new hope for individuals struggling with conditions like AUD or substance use disorder.

The Food Industry Is Already Feeling the Impact

The growing use of GLP-1 drugs beyond diabetes management is even gaining the attention of the food and beverage industry. Companies that sell ultra-processed snacks, processed food, sugary sodas, artificially-flavored drinks, and alcohol are particularly concerned about sales declines.

Some companies are therefore focused on creating products that will address the taste and nutritional needs of health-conscious consumers. They’re adjusting their product lines to include items with high protein and fiber content, as well as offering healthy options in smaller portion sizes.

Taking the Next Step: Talk To Your Doctor to Find Out If You Should Be on GLP-1 Medication

As the food industry adapts to this shift in consumer behavior, individuals may be wondering whether GLP-1 treatments are right for them. GLP-1 receptor agonists are currently prescribed for people with type 2 diabetes, those with obesity (defined as individuals with a BMI of 30 or higher, or a BMI of 27 with obesity-related health conditions such as hypertension or high cholesterol),.

However, determining whether GLP-1 therapy is the best choice for someone should be based on a detailed talk with their doctor that includes a complete review of the person’s medical history, their health status, and clarity about their long-term treatment goals.

Every drug carries risks, and GLP-1 medications are no different. That’s why it’s important to keep in mind that while GLP-1s offer promising health benefits, their effectiveness can vary from person to person. Factors such as an individual’s metabolism, baseline nutrition, and underlying medical conditions can influence how well they work.

One of the concerns with GLP-1s is the potential for developing nutritional deficiencies. Because these drugs suppress a person’s appetite, individuals need to ensure they get an adequate amount of nutrients for proper health. Additionally, significant weight loss without sufficient protein intake and regular physical activity can contribute to muscle loss. Yet another consideration when starting on GLP-1s is the possibility of weight regain after stopping the medication. Thus it is important to design a healthy and sustainable lifestyle plan alongside any pharmacological treatment.

 

Personalized Guidance from Legacy Community Health’s Diabetes Care Experts

At Legacy Community Health, we provide comprehensive support for patients considering or currently using GLP-1 medications for type 2 diabetes or weight-loss treatment, offering a multidisciplinary team approach to personalized care:

• Endocrinology specialists – Access to doctors who specialize in the care of endocrine disorders such as diabetes.
• Pharmacy support – Licensed pharmacists who provide education and medication management.
• Goal setting and monitoring tools – Healthcare tracking tools and tips on how to best use them.
• Diabetes education – Access to experienced and caring patient educators, plus diabetes management classes, patient handouts and web resources
• Eating healthy support – Registered dieticians who teach patients how to identify and make healthy food choices

Through our holistic approach, we help patients navigate the complexities of GLP-1 therapy, ensuring they achieve the best possible outcomes while minimizing potential side effects.

Visit us online or call (832) 548-5000 to schedule an appointment. Together, we can ensure you receive the guidance and support needed to make informed decisions about GLP-1 therapy.